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A PHARMACEUTICAL COMBINATION INCLUDING A HISTONE DEACETYLASE 4 (HDAC4) SILENCING AGENT FOR TREATING CANCER
A PHARMACEUTICAL COMBINATION INCLUDING A HISTONE DEACETYLASE 4 (HDAC4) SILENCING AGENT FOR TREATING CANCER
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机译:包括组蛋白去乙酰化酶4(HDAC4)减毒剂的药物组合物,用于治疗癌症
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摘要
The invention is based on a finding that silencing HDAC4gene sensitizes cancer cells for apoptosis-inducing activity of certain small molecule chemotherapeutic agents. Thus, the invention is directed to a respective combination therapy, sensitization method and pharmaceutical compositions.
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