首页>
外国专利>
CLEAVABLE MODIFICATIONS TO REDUCIBLE POLY(AMIDO ETHYLENIMINE)S TO ENHANCE NUCLEOTIDE DELIVERY
CLEAVABLE MODIFICATIONS TO REDUCIBLE POLY(AMIDO ETHYLENIMINE)S TO ENHANCE NUCLEOTIDE DELIVERY
展开▼
机译:对可还原聚(酰胺基乙撑亚胺)进行可裂解的修饰以增强核苷酸的传递
展开▼
页面导航
摘要
著录项
相似文献
摘要
Improved poly(amido ethylenimine) copolymers for gene delivery are disclosed. One illustrative embodiment includes polyethylene glycol (PEG) covalently bonded to a branched poly (triethyenetetramine/cystamine bisacrylamide) copolymer (poly (TETA/CBA) ). The polyethylene glycol can be linear or branched. Another illustrative embodiment includes an RGD peptide covalently bonded to the poly (TETA/CBA) -PEG conjugate. Still another illustrative embodiment includes a method of using these compositions for transfecting a cell with a nucleic acid.
展开▼