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Antibodies useful for inhibiting the activity of metalloproteins and pharmaceutical compositions containing the antibodies
Antibodies useful for inhibiting the activity of metalloproteins and pharmaceutical compositions containing the antibodies
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机译:用于抑制金属蛋白活性的抗体和含有该抗体的药物组合物
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摘要
The present invention relates to a compound having the general Formula (I): wherein: m and n are each independently an integer from 1 to 6; X1-X3 and Y1-Y3 are each independently O or S; R1-R3 are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and R is (CH2)x-C(O)NR(CH2)y-NRR whereas: x and y are each independently an integer from 1 to 6; and R and R are each independently selected from the group consisting of hydrogen, alkyl, and cycloalkyl; and to an antibody comprising an antigen recognition region capable of specifically binding the above compound.
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机译:本发明涉及具有通式(I)的化合物:其中:m和n分别独立地为1至6的整数;和X1-X3和Y1-Y3分别独立地为O或S; R 1 -R 3各自独立地选自氢,烷基和环烷基; R为(CH 2)x -C(O)NR(CH 2)y -NRR,其中:x和y分别独立地为1〜6的整数。 R 1和R 2各自独立地选自氢,烷基和环烷基;本发明涉及包含能特异性结合上述化合物的抗原识别区的抗体。
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