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NANODIAMOND PARTICLE AND METHOD OF MANUFACTURING THE SAME, AND FLUORESCENT MOLECULAR PROBE AND METHOD OF ANALYZING STRUCTURE OF PROTEIN
NANODIAMOND PARTICLE AND METHOD OF MANUFACTURING THE SAME, AND FLUORESCENT MOLECULAR PROBE AND METHOD OF ANALYZING STRUCTURE OF PROTEIN
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机译:纳米金刚石颗粒及其制造方法,荧光分子探针和蛋白质结构分析方法
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摘要
A nanodiamond particle including an NV center having ODMR intensity enhanced, of which surface is modified with a functional group containing a heteroatom, is provided. This nanodiamond particle as being chemically modified can serve for a fluorescent molecular probe which can be made use of in a biological system. By tracking a rotational motion of the NV center included in this fluorescent molecular probe, structural change of a protein can be analyzed in real time. The functional group containing a heteroatom can be at least any functional group of a hydroxyl group and a hydroxyalkyl group, or a carboxyl group.
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