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Protein charge regulator and protein-encapsulating polymer micelle complex
Protein charge regulator and protein-encapsulating polymer micelle complex
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机译:蛋白质电荷调节剂和包裹蛋白质的聚合物胶束复合物
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摘要
The present invention provides a protein delivery means (e.g., a polyion complex) which allows efficient introduction into cells (particularly into the cytoplasm), is highly stable in serum, and is also widely applicable. The polyion complex of the present invention comprises a cationic polymer having a polycation moiety and a charge-conversional protein whose overall charge is converted from basic or neutral to acidic by a specific charge regulator.
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