compound, composition, method for treating cancer in a mammal, method for inhibiting angiogenesis in a mammal, and inhibiting a hedgehog signaling pathway in a cell, process for preparing a compound

摘要

The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein A, X, Y R1, R2, R3, R4, m and n are as described herein.