Compounds derived from benzene-1-sulfonamide, Orphan receptor modulators retinoideo gamma; Pharmaceutical composition that comprises; and its use for the treatment of cystic fibrosis, Asthma, bronchitis, allergic rhinitis, rheumatoid arthritis, Osteoarthritis, pancreatitis and ulcerative colitis, among Other Diseases.

摘要

The present invention is directed to novel retinoid-related orphan receptor gamma (RORγ) modulators, processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by RORγ.