Azaindolinas substituted Compounds, inhibitors of the binding of SMAC Protein inhibitor of Apoptosis Protein (IAP) and / or inhibitors of the binding of Protein to the activated caspase IAP; Pharmaceutical composition that comprises; a method for treating cancer or improve its use; and P For The therapeutic and / or prophylactic Treatment of cancer.

摘要

Disclosed are compounds of Formula (I), or pharmaceutically acceptable salts thereof, wherein W, Y, Z, R1, R2, R3 and R4 are as described in this application, and methods of using the compounds in the treatment of cancer.