With piridilo substituted heteroaryl compounds as kinase modulators; Pharmaceutical composition that comprises; and its use for the treatment of an inflammatory or Autoimmune Disease such as Crohn's disease, multiple sclerosis, systemic lupus erythematosus, and Gout Gouty arthritis.

摘要

Compounds having the following formula (I) or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.