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Antibody constructs for binding domains for cdh19 and cd3, copositions same, methods of producing same and uses thereof
Antibody constructs for binding domains for cdh19 and cd3, copositions same, methods of producing same and uses thereof
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机译:用于cdh19和cd3的结合结构域的抗体构建体,其共同构成,其制备方法及其用途
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摘要
The present invention provides to an antibody construct comprising a first human binding domain capable of binding to human CDH19 on the surface of a target cell and a second domain capable of binding to human CD3 on the surface of a T cell. Moreover, the invention relates to a nucleic acid sequence encoding the antibody construct, a vector comprising said nucleic acid sequence and a host cell transformed or transfected with said vector. Furthermore, the invention relates a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.
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