Indazol - 3 - carboxamidas and their use as inhibitors of the Wnt Signalling Pathway / B catenin

摘要

Relates to compounds of formula (i), wherein: R1, R2 and R4 are independently h, alkyl halide, C1 - CN, - 9, and ocf3 - CF3, among others; R3 is carbociclilr6, arilr6, heterociclilr6, among others; R5 is - (alkyl C1 - ncarbociclilr7 - (9), C1 - 9 nheterociclilr7, alkyl (alkyl) - C1 - 9) narilr7, among other S; R6 is 1 - 5 substituents selected from h, alkyl halide, Amine C1 - 9,,Among others; R7 is 1 - 5 C1 alkyl substituents selected from h, - 9, - ocf3, - CN, - CF3, among others; n is 0 OR 1. It also relates to a Pharmaceutical composition. These compounds are useful for the treatment of cancer, Diabetic Retinopathy, rheumatoid arthritis, viral or fungal infection