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PROTEOMIC PROFILE CARRIED OUT BY MASS SPECTROMETRY FOR DETECTING CEREBRAL TUMORS

机译:质谱法检测脑肿瘤的蛋白质组学特征

摘要

The invention relates to an assessment method for identifying bio-markers by analyzing the protein expression profile in serum samples from patients with glioblastoma. According to the invention, the method consists in preparing and providing the chips after which the measuring protocol is applied to the protein samples, followed by the analysis of data wherefrom a group of relevant seric clusters is identified, a set of 4 bio-markers S100A8, S100A9, CXCL4, CXCL7 being selected, the said bio-markers showing significant statistic differences between the patients with cerebral tumors and the healthy subjects.
机译:本发明涉及通过分析来自成胶质细胞瘤患者血清样品中蛋白质表达谱来鉴定生物标志物的评估方法。根据本发明,该方法包括准备和提供芯片,然后将测量方案应用于蛋白质样品,随后进行数据分析,从中识别出一组相关的丝氨酸簇,一组4个生物标记物S100A8选择S100A9,CXCL4,CXCL7,所述生物标志物在患有脑肿瘤的患者和健康受试者之间显示出显着的统计学差异。

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