CHIMERIC EMPTY VIRAL-LIKE PARTICLES DERIVED FROM THE INFECTIOUS BURSAL DISEASE VIRUS (IBDV), PROCESS FOR THEIR PRODUCTION AND APPLICATIONS

摘要

The chimeric empty viral-like particles derived from the infectious bursaldisease virus (IBDV) are formed by the assembly of fusion proteins comprisinga region A comprising an IBDV pVP2 protein or a "1-n" fragment of said IBDVpVP2, wherein "n" is an integer comprised between 441 and 501, and a region Bcomprising a heterologous polypeptide comprising a polypeptide of interest,such as a polypeptide useful for prophylactic, therapeutic or diagnosticpurposes.