NEW CYCLIC LIPOPEPTIDE ANTIBIOTIC LOCILLOMYCIN (LOCILLOMYCIN-A, LOCILLOMYCIN-B, LOCILLOMYCIN-C) AND METHODS OF MAKING AND USING THE SAME

摘要

This invention provides new cyclic lipopeptide antibiotic Locillomycin(Locillomycin-A,Locillomycin-B, Locillomycin-C) that display very strong antifungal,antibacterial, antivirusactivities in a variety of contexts in vitro; methods of making and using thecompounds, wherein Locillomycin-A, Locillomycin-B and Locillomycin-C arederived and purifiedfrom the culture of Bacillus subtilis Bs916.