A computer-based method and system assists users performing medical imaging studies, such as echocardiograms. While the user manipulates the imaging device on an individual, the system automates image processing, relieving the user from the need to simultaneously operate an application and an imaging device. The system assesses an organ system, then through comparison with other imaging data sets, generates an evaluative assessment of the organ system. The system becomes increasingly image-aware and content-aware during an evaluation, and by sequential comparisons against progressive data sets, refines an evaluative assessment.
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