IMPROVED REPRODUCIBILITY OF IMPACT-BASED IONIZATION SOURCE FOR LOW AND HIGH ORGANIC MOBILE PHASE COMPOSITIONS USING A MESH TARGET

摘要

An ion source is disclosed comprising one or more nebulizers and one or more mesh or grid targets. The one or more nebulizers are arranged and adapted to emit, in use, a stream predominantly of droplets which are caused to impact upon the one or more mesh or grid targets and to ionize the droplets to form a plurality of ions.