首页> 外国专利> CRYSTALLINE FORMS OF (1S)-1-5-({3-(2-METHYLPYRIDIN-3-YL)OXY-5-(PYRIDIN-2-YLSULFANYL)PYRIDIN-2-YL}AMINO)-1,2,4-THIADIAZOL-3-YLETHANE-1,2-DIOL

CRYSTALLINE FORMS OF (1S)-1-5-({3-(2-METHYLPYRIDIN-3-YL)OXY-5-(PYRIDIN-2-YLSULFANYL)PYRIDIN-2-YL}AMINO)-1,2,4-THIADIAZOL-3-YLETHANE-1,2-DIOL

机译:(1S)-1- [5-({3-[(2-甲基吡啶基-3-基)氧基] -5-(吡啶基-2-嘧啶基)吡啶基-2-基}氨基)-1,2的晶体形式,4-噻二唑-3-基]乙烷-1,2-二醇

摘要

The present invention relates to crystalline polymorph forms of (1S)-1-[5-({3-[(2-methylpyridin-3-yl)oxy]-5-(pyridin-2-ylsulfanyl)pyridin-2-yl}amino)-1,2,4-thiadiazol-3-yl]ethane-1,2-diol, to pharmaceutical compositions comprising such crystalline polymorph forms, and to processes for preparing them. The invention further relates to methods of treatment of diabetes related disorders comprising administering such solid-state forms or compositions thereof to a subject, and to use of such crystalline polymorph forms in the manufacture of medicaments.
机译:本发明涉及(1S)-1- [5-({3-[(2-甲基吡啶-3-基)氧基] -5-(吡啶-2-基硫烷基)吡啶-2-基}的结晶多晶型物形式。氨基)-1,2,4-噻二唑-3-基]乙烷-1,2-二醇,包含这种结晶多晶型物形式的药物组合物及其制备方法。本发明进一步涉及治疗与糖尿病有关的疾病的方法,该方法包括将这种固态形式或其组合物施用于受试者,并且涉及这种结晶多晶型物形式在药物生产中的用途。

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