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Composition comprising carnosic acid having anti-Respiratory syncytial virus activity

机译:包含具有抗呼吸道合胞病毒活性的肌酸的组合物

摘要

The present invention relates to a composition which has an anti-respiratory syncytial virus (RSV) activity and includes a carnosic acid as an active ingredient. More specifically, the carnosic acid isolated from rosemary extracts shows an antiviral effect on both A-type and B-type RSV. The carnosic acid is more effective than rivavirin which is used as a conventional treatment composition. The present invention can significantly suppress the virus gene expression without generating I-type interferon, inhibit the infection and replication of RSV, and affect cell survival. Accordingly, the composition can be utilized as a pharmaceutical composition for prevention and treatment of respiratory disease or as a dietary supplement.
机译:本发明涉及一种具有抗呼吸道合胞病毒(RSV)活性并包含肌酸作为活性成分的组合物。更具体地说,从迷迭香提取物中分离出的鼠尾草酸对A型和B型RSV均显示抗病毒作用。肌酸比用作常规治疗组合物的利伐韦林更有效。本发明可以在不产生I型干扰素的情况下显着抑制病毒基因的表达,抑制RSV的感染和复制,并影响细胞存活。因此,该组合物可以用作预防和治疗呼吸道疾病的药物组合物或饮食补充剂。

著录项

  • 公开/公告号KR20150045259A

    专利类型

  • 公开/公告日2015-04-28

    原文格式PDF

  • 申请/专利权人 경희대학교 산학협력단;

    申请/专利号KR20130124743

  • 发明设计人 인경수;장대식;신한보;

    申请日2013-10-18

  • 分类号A61K31/08;A61K31/05;A61K31/185;A61K31/192;A61P31/12;

  • 国家 KR

  • 入库时间 2022-08-21 15:00:16

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