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method for dedifferentiating adult cell to induced pluripotent stem cell using electromagnetic field

机译:电磁场使成体细胞分化为诱导性多能干细胞的方法

摘要

the present invention is the electromagnetic field using adult cells to induced pluripotent stem cells to differentiate into reverse a method. Induced pluripotent stem cells by a method of de-differentiation using an electromagnetic field according to the present invention, the efficiency of de-differentiation into pluripotent stem cells and adult cells induce excellent induce pluripotent stem cells can be easily obtained. Further, the induced pluripotent stem cells is prepared in a high expression level of de-differentiation factors, when implanted in the mouse, the ability to differentiate all shown. Thus, the reprogrammed induced pluripotent stem cells to be useful and studies of cell therapy development and regenerative medicine field. ;
机译:本发明是利用成年细胞诱导多能干细胞分化为反向电磁场的方法。通过根据本发明的使用电磁场的去分化方法诱导多能干细胞,可以容易地获得去分化为多能干细胞和成年细胞诱导优异的诱导多能干细胞的效率。此外,以高表达水平的去分化因子制备诱导的多能干细胞,当将其植入小鼠中时,其分化能力全部显示出来。因此,重新编程的诱导多能干细胞将有用并研究细胞疗法的发展和再生医学领域。 ;

著录项

  • 公开/公告号KR101548534B1

    专利类型

  • 公开/公告日2015-09-02

    原文格式PDF

  • 申请/专利权人 동국대학교 산학협력단;

    申请/专利号KR20130124784

  • 发明设计人 박정극;백순봉;김종필;

    申请日2013-10-18

  • 分类号C12N5/074;C12N13/00;

  • 国家 KR

  • 入库时间 2022-08-21 14:57:44

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