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METHOD OF TREATING RECURRENT NON-SMALL CELL LUNG CANCER

机译:治疗复发性非小细胞肺癌的方法

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, oncology and aims at treating recurrent non-small cell lung cancer (NSLC). The treatment involves a beam therapy (BT) combined with a chemotherapy (CT). The BT having a total boost dose of no more than 64 Gy is conducted 5 days a week for 5 weeks: first, a single boost dose of 3.0 Gy× once a day to the total boost dose of no more than 40 Gy, and then the single boost dose of 1.2 Gy× twice a day. Herewith, 2.5 hours before the irradiation, 10 45-minute sessions of a hyperthermia are performed 2 times a day at temperature 42-44°C. The chemotherapy follows: on the 1st and 8th days of the irradiation - gemcitabine 1000 mg/m2, on the 1st day - cysplatine 70 mg/m2, within the two cycles every 2 weeks.;EFFECT: method improves a survival rate in the patients suffering recurrent NSLC by increasing the loco-regional control, preventing remote metastases and reducing a rate thereof.;1 ex
机译:技术领域本发明涉及医学,肿瘤学并且旨在治疗复发性非小细胞肺癌(NSLC)。治疗涉及束疗法(BT)结合化学疗法(CT)。总增强剂量不超过64 Gy的BT每周进行5天,持续5周:首先,每天一次3.0 Gy×的增强剂量到不超过40 Gy的总增强剂量,然后每天两次1.2 Gy×的单次加强剂量。因此,在照射前2.5小时,在42-44℃的温度下每天进行两次10次热疗,每次45分钟。化疗如下:在辐射的第1 和第8 天-吉西他滨1000 mg / m 2 在1 st 天-cysplatine 70 mg / m 2 ,每2周两个周期内;效果:该方法通过提高局部区域控制来提高复发性NSLC患者的生存率,防止远处转移并降低其发生率。

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