首页> 外国专利> APPLICATION OF CHITOSAN DERIVATIVE FOR SELECTIVE DELIVERY OF MEDICATIONS AND BIOLOGICALLY ACTIVE COMPLEXES

APPLICATION OF CHITOSAN DERIVATIVE FOR SELECTIVE DELIVERY OF MEDICATIONS AND BIOLOGICALLY ACTIVE COMPLEXES

机译:壳聚糖衍生物在药物和生物活性复合物选择性递送中的应用

摘要

FIELD: medicine.SUBSTANCE: invention relates to medicine, veterinary and food industry and consists in the application of a chitosan derivative, modified by a residue of fatty or amino acid and anhydride of succinic acid as a part of the composition, which contains a medication or a biologically active complex, intended for the delivery of the said medication or the said biologically active complex into an organism. The invention also relates to the composition, which contains the medication or the biologically active complex, containing the said chitosan derivative.EFFECT: invention makes it possible to provide the medication or the biologically active complex, which contains the chitosan derivative, with high trasndermal and membrane permeability, increased sorption capacity, soluble in a wide pH range.40 cl, 7 dwg, 1 tbl, 2 ex
机译:技术领域本发明涉及医药,兽医和食品工业,其包含壳聚糖衍生物的应用,所述壳聚糖衍生物被脂肪或氨基酸残基和琥珀酸的酸酐作为组合物的一部分改性,其中含有药物或用于将所述药物或所述生物活性复合物递送到生物体中的生物活性复合物。本发明还涉及包含所述壳聚糖衍生物的包含药物或生物活性复合物的组合物。效果:本发明使得提供包含壳聚糖衍生物的药物或生物活性复合物具有高的透皮性和膜渗透性增强,吸附能力增强,可在宽pH范围内溶解.40 cl,7 dwg,1 tbl,2 ex

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