DIAGNOSTIC TECHNIQUE AND KIT FOR DIAGNOSING GLOMERULONEPHITIS IN CAT

摘要

FIELD: medicine.SUBSTANCE: group of inventions refers to biotechnology. A diagnostic technique for glomerulonephritis in a cat provides measuring an expression level of one or more biomarkers specified in a group consisting of lumican; a collagen alpha 1 chain (III), version 12; decorin; secreted related frizzled protein 2; retinol-binding protein 5; MMP-2; MMP-7 and MMP-19 in a biological sample taken from the cat. A considerable difference in the expression of one or more biomarkers in the sample as compared to the reference expression in the sample taken from a healthy animal testifies to the presence of a renal disorder. The group of inventions also contains a kit for implementing the above technique, also applicable for diagnosing nucleotide sequences complementary to the above genes.EFFECT: diagnosing glomerulonephritis with the use of this group of inventions enables the early detection and prediction of glomerulonephritis.22 cl, 16 dwg, 4 tbl, 6 ex