首页> 外国专利> METHOD OF PREDICTING RISK OF DEVELOPMENT OF NEUROLOGICAL DEFICIENCY IN FULL-TERM NEW-BORN BABIES WITH HYPOXIC-ISCHEMIC BRAIN INJURY

METHOD OF PREDICTING RISK OF DEVELOPMENT OF NEUROLOGICAL DEFICIENCY IN FULL-TERM NEW-BORN BABIES WITH HYPOXIC-ISCHEMIC BRAIN INJURY

机译:预测缺氧缺血性脑损伤足月新生婴儿的神经缺陷发展风险的方法

摘要

FIELD: medicine.SUBSTANCE: method of predicting risk of development of neurological deficiency in full-term new-born babies with hypoxic-ischemic brain injury includes clinical and neurosonographic detection of severe manifestations on 2-12 day of child's life. For this purpose MRT is carried out in mode of diffusion-weighted imaging, determined are: average value of measured diffusion coefficient (AVMDC) of white matter of brain at the level of anterior and posterior horns of lateral ventricles, bodies of lateral ventricles of both hemispheres and AVMDC of gray matter of cortex of frontal lobes and lenticular nuclei of both hemispheres. If AVMDC of brain white matter is from 1.62×10mm/sec to 1.40×10mm/sec, of gray substance of brain from 1.30×10mm/sec 1.17×10mm/sec, absence in future of stable neurological deficiency and development of functional disorders in child is predicted, which corresponds to cerebral ischemia of II degree. If AVMDC of white matter of brain is from 1.30×10mm/sec to 0.69×10mm/sec, of gray substance of brain is from 1.07×10mm/sec to 0.64×10mm/sec, development of stable neurological deficiency is predicted, which corresponds to cerebral ischemia of III degree.EFFECT: method ensures high accuracy of determination of degree of brain tissue ischemia, which makes it possible to predict its outcome - further neurological development of child, absence or formation of neurological deficiency in them.5 ex, 1 tbl
机译:领域:医学。研究对象:预测新生儿缺氧缺血性脑损伤婴儿神经系统缺损发展风险的方法包括临床和神经超声检查对儿童生命中2-12天的严重表现。为此,MRT以扩散加权成像的方式进行,确定如下:在侧脑室的前角和后角处,脑白质的实测扩散系数(AVMDC)平均值额叶皮层灰质和两个半球的晶状体核的半球和AVMDC。如果脑白质的AVMDC为1.62×10mm / sec至1.40×10mm / sec,脑灰质物质为1.30×10mm / sec 1.17×10mm / sec,那么将来就不会出现稳定的神经功能缺损和功能障碍的发展。可以预测孩子,它相当于II度脑缺血。如果脑白质的AVMDC为1.30×10mm / sec至0.69×10mm / sec,脑灰质为1.07×10mm / sec至0.64×10mm / sec,则可以预测到稳定的神经功能缺损的发展,这与效果:该方法可确保高度确定脑组织缺血程度,因此可以预测其结局-儿童进一步神经系统发育,缺乏或形成神经系统缺陷。5ex,1 tbl

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