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METHOD OF OBTAINING NANOPARTICLES OF BORON NITRIDE FOR DELIVERY OF ANTI-TUMOUR MEDICATIONS

机译:获取用于治疗抗肿瘤药物的氮化硼的纳米粒子的方法

摘要

FIELD: medicine.SUBSTANCE: spherical nanoparticles of boron nitride with size 50-300 nm with developed external surface are synthesised by method of chemical precipitation from gas phase with application of reaction and transport gases, as well as powder mixtures, which consist of amorphous boron and reagent-oxidants, dispersion of agglomerates of obtained boron nitride nanoparticles by method of ultrasonic processing, saturation of boron nitride nanoparticles with anti-tumour medication by method of sorption and washing of nanoparticles in distilled water are carried out.EFFECT: method makes it possible to improve efficiency of anti-tumour chemotherapy due to increased activity of absorption of nanocontainers with anti-tumour medication by cells, prevention of toxicity of nanocontainers for cells.19 cl, 2 ex, 2 tbl
机译:领域:医学领域:通过应用反应和输送气体从气相中化学沉淀的方法,以及由非晶态硼组成的粉末混合物,合成了具有发达外表面的尺寸为50-300 nm的氮化硼球形纳米颗粒试剂和氧化剂,通过超声处理获得的氮化硼纳米颗粒的附聚物的分散,通过吸附和洗涤纳米颗粒在蒸馏水中的方法对氮化硼纳米颗粒进行抗肿瘤药物的饱和处理。效果:该方法使之成为可能通过增加抗肿瘤药物被细胞吸收纳米容器的活性来提高抗肿瘤化学疗法的效率,防止纳米容器对细胞的毒性。19cl,2 ex,2 tbl

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