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Composition of biocompatible microparticles of alginic acid for the controlled release of active ingredients by intravenous administration

机译:海藻酸生物相容性微粒的组成,可通过静脉内给药控制活性成分的释放

摘要

Composition of biocompatible microparticles of alginic acid for the controlled release of active ingredients by intravenous administration. The invention relates to a biocompatible composition which comprises microparticles of alginic acid or its salts and an active ingredient. More particularly, the invention relates to microparticles for the encapsulation of an active ingredient to be administered intravenously to a patient who needs it. These microparticles are of a combination of size sufficient to increase the half-life or survival of the active ingredient in blood, with a low uptake in the liver and a fast cell clearance when administered intravenously.
机译:海藻酸的生物相容性微粒的组成,用于通过静脉内给药控制活性成分的释放。本发明涉及一种生物相容性组合物,其包括藻酸或其盐的微粒和活性成分。更具体地,本发明涉及用于封装活性成分的微粒,该活性成分将静脉内给予需要其的患者。这些微粒的大小组合足以增加活性成分在血液中的半衰期或存活率,在静脉内给药时肝脏吸收率低,细胞清除速度快。

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