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METHOD FOR STEREOSELECTIVE SYNTHESIS OF BICYCLIC HETEROCYCLES

机译:双环杂环立体合成的方法

摘要

The present invention relates to a process for the stereoselective preparation of compounds of general formula (I) and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids and bases, which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for the treatment of diseases, particularly tumoral diseases as well as benign prostatic hyperplasia (BPH), diseases of the lungs and airways.
机译:本发明涉及立体选择性地制备通式(I)的化合物及其盐,特别是其与无机或有机酸和碱的生理上可接受的盐的方法,该方法具有有价值的药理特性,尤其是对信号的抑制作用酪氨酸激酶介导的转导,其在疾病,特别是肿瘤疾病以及良性前列腺增生(BPH),肺和气道疾病的治疗中的用途。

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