The invention relates to the application of pentacyclic triterpenoid saponins, extracted from the plant of Silene viscidula, which are used to manufacture the anti-diabetic medicaments. Having screened and researched the plants and the compounds massively, the inventors found that the compounds of pentacyclic triterpenoid saponins extracted and purified from Silene viscidula (hereinafter called Wacao saponnins), have strong effects on hyperglycemia, especially for the compounds that have mother nuclei of sinocrassulosides, which can be used to manufacture anti-diabetic medicaments.
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