DETECTION METHOD OF BCR-ABL INHIBITOR RESISTANCE-ASSOCIATED MUTATIONS, AND DATA ACQUISITION METHOD FOR PREDICTING BCR-ABL INHIBITOR RESISTANCE USING THE SAME

摘要

PROBLEM TO BE SOLVED: To detect mutations associated with BCR-ABL inhibitor resistance in chronic myeloid leukemia and the like with higher accuracy.SOLUTION: A step of amplifying a region comprising a fusion site comprised in BCR-ABL fusion genes and a mutation site involved in BCR-ABL inhibitor resistance using a biological specimen collected from a subject; and a step of determining the genotype of the mutation site involved in the above BCR-ABL inhibitor resistance using a nucleic acid amplified in the above step are comprised.SELECTED DRAWING: None