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ASTROCYTE DIFFERENTIATION INDUCER, AND GFAP EXPRESSION INDUCER

机译:星形细胞分化诱导剂和GFAP表达诱导剂

摘要

PROBLEM TO BE SOLVED: To provide an astrocyte differentiation inducer which induce differentiation of a neural stem cell at a high rate, and a glial fibrillary acidic protein (GFAP) expression inducer.SOLUTION: There is provided an astrocyte differentiation inducer that induces differentiation of a neural stem cell into astrocyte at a high rate, which contains piceatannol being a type of a stilbene compound of polyphenol having a stilbene skeleton as an active ingredient. Further, there is also provided a GFAP expression inducer that induces expression of GFAP in the neural stem cell at high-rate, which contains piceatannol as an active ingredient. Piceatannol may be a chemical synthetic product or may be derived from a natural material such as a plant.SELECTED DRAWING: None
机译:解决的问题:提供一种星形胶质细胞分化诱导剂,其以高速率诱导神经干细胞的分化,并提供神经胶质纤维酸性蛋白(GFAP)表达诱导剂。神经干细胞以高速率进入星形胶质细胞,其中含有皮甲三醇(piceatannol),即一种以lb骨架为活性成分的多酚a化合物。此外,还提供了一种以高水平诱导神经干细胞中的GFAP表达的GFAP表达诱导剂,其含有皮卡丹酚作为有效成分。 Piceatannol可以是化学合成产品,也可以来自天然物质(例如植物)。

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