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USE OF CCI-779 AS ANTINEOPLASTIC AGENT

机译:使用CCI-779作为抗肿瘤药

摘要

PROBLEM TO BE SOLVED: To provide the use of CCI-779 as an antineoplastic agent, and particularly for neoplasms which are refractory to standard therapy, or for patients for whom standard therapy is not appropriate.SOLUTION: The present invention provides pharmaceutical compositions containing rapamycin 42-ester with 3-hydroxy-2-(hydroxymethyl)-2-methylpropionic acid (CCI-779) for use in treatment of refractory renal cell cancer in a mammal in which a neoplasm progressed following treatment with standard chemotherapy appropriate for the neoplasm.SELECTED DRAWING: None
机译:解决的问题:提供CCI-779作为抗肿瘤药的用途,特别是对于标准疗法难以治疗的肿瘤,或不适用于标准疗法的患者。解决方案:本发明提供了包含雷帕霉素的药物组合物具有3-羟基-2-(羟甲基)-2-甲基丙酸(CCI-779)的42酯,用于治疗哺乳动物的难治性肾细胞癌,该哺乳动物在经过适合于该肿瘤的标准化学疗法治疗后进展为肿瘤。选定的图纸:无

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