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Means and methods for universal calibration of anti-factor Xa test

机译:通用校准抗因子Xa测试的方法和方法

摘要

The present invention relates to diagnostic means and methods in the field of coagulation tests. In particular, it is a method for determining anticoagulant activity induced by a first anticoagulant in a sample of a subject, measuring the first factor Xa in said body fluid test sample of said subject Measuring a second factor Xa activity in at least one calibration sample comprising a predetermined anticoagulant activity for the second anticoagulant, and determining the first and second measured factor Xa activities Calculating a universal parameter for anticoagulant activity contained in the test sample based on and comparing said parameter for anticoagulant activity with a predetermined range of predicted anticoagulant activity for at least three anticoagulants. Regarding the method. In addition, computer program code to support the methods and systems and kits for performing the methods are provided. [Selection figure] None
机译:本发明涉及凝血测试领域中的诊断手段和方法。特别地,本发明是一种用于确定由受试者的样品中的第一抗凝剂诱导的抗凝活性,测量所述受试者的所述体液测试样品中的第一因子Xa,以及测量至少一个校准样品中的第二因子Xa活性的方法,包括:确定第二种抗凝剂的预定抗凝活性,并确定第一和第二测量因子Xa活性基于上述抗凝活性的参数并将其与预测抗凝活性的预定范围相比较,计算测试样品中所含抗凝活性的通用参数至少三种抗凝剂。关于方法。另外,提供了支持该方法和系统的计算机程序代码以及用于执行该方法的套件。 [选择图]无

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