System and method for monitoring brain metabolism and activity using electroencephalogram and optical imaging

摘要

Systems and methods for monitoring and / or controlling the state of a subject's brain are provided. In certain embodiments, the method obtains physiological data from a sensor, including an electrophysiological sensor and an optical sensor, and uses the physiological data from the electrophysiological sensor to perform brain activity on the subject. And a step of identifying a burst suppression state represented by a burst suppression period and a burst period using the time series signal. The method further includes using the data from the optical sensor to calculate a parameter associated with the burst suppression state representing at least one of a metabolic process and a hemodynamic process; the parameter, the time series signal, and Using a burst period to estimate a response function that represents a change in the parameter over time correlated to the burst in the burst suppression period. The method further includes controlling the treatment using the response function to produce a target burst suppression condition. [Selection] Figure 5