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Methods utilizing insect model to measure the intestinal absorption of the compound

机译:利用昆虫模型测量化合物肠道吸收的方法

摘要

In order to improve chemical compound screening procedure/the process in early creation glaze processing, the Vertebrata, the insect screening model in order to measure the stomach tube absorption of the various chemical compounds in the especially person is offered. There are many advantages as the tool of judgment process, speeding up the process of the medicine screening, makes the decrease factor of anaphase phase small from the fact that as for the insect model reliability is higher than the existing in vitro model, in comparison with technology until recently. In addition, it means also to decrease the number of mammals which become sacrifice at phase of the creation glaze.
机译:为了改善化合物筛选程序/早期釉处理中的过程,提供了Vertebrata昆虫筛选模型,以测量特别是人中各种化合物在胃管中的吸收。与昆虫模型的可靠性相比,昆虫模型的可靠性比现有模型高,因此作为判断过程的工具,加快药物筛选过程,使后期阶段的减少因子变小,具有许多优势。技术直到最近。另外,这还意味着减少在造釉阶段变成牺牲的哺乳动物的数量。

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