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N- (2,2- difluoroethyl) methods for preparing starting from prop-2-en-1-amine 2,2-difluoroethyl amine derivative
N- (2,2- difluoroethyl) methods for preparing starting from prop-2-en-1-amine 2,2-difluoroethyl amine derivative
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机译:从丙-2-烯-1-胺2,2-二氟乙基胺衍生物开始制备的N-(2,2-二氟乙基)方法
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摘要
Process for the preparation of 2,2-difluoro-ethyl amine derivative represented by containing the step (ii) and step (i), the formula (IV). In step (i), optionally in the presence of an inorganic base or an organic base of formula (II, formula (I) and N- (2,2- difluoroethyl) prop-2-en-1-amine can be reacted with a compound represented by 2 -E) A-CH, and to produce a compound of formula (III). In step (ii), the compound of formula (III) removing (de-allylated) allyl group [wherein, E and A in the formula (III) and (IV) Formula (II), formula I have the meanings indicated herein]. [Formula 1]
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