The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.
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机译:本发明涉及包含氨基酸序列X1DGRX5GF(SEQ ID NO:1)的膀胱癌特异性配体肽,及其用途,例如用于影像学检测以诊断膀胱,肿瘤定位以指导经尿道膀胱切除术癌症,对膀胱癌进行影像学检测以进行初始治疗后的随访,以取代或补充昂贵的膀胱镜检查,对转移性膀胱癌进行影像学检测以及对浅表和转移性膀胱癌进行靶向治疗。
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