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MONITORING A DYNAMIC SYSTEM BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY
MONITORING A DYNAMIC SYSTEM BY LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY
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机译:液相色谱-质谱联用监测动态系统
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摘要
The present invention provides a method for monitoring of profile changes of components in a dynamic system such as a cell-free in vitro protein synthesis system by using liquid chromatography (LC) combined with mass spectrometry (MS). In an additional aspect, this invention provides a method for enhancing the yield and/or reproducibility in a cell-free protein synthesis system by modulating the level and/or activity of a protein component that has regulatory effects on the system.
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