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Cell Separation and Collection Membrane, and Culturing Sheet, Culturing Device, and Cell Separation and Collection Method Using Same

机译:细胞分离收集膜,培养片,培养装置以及使用其的细胞分离收集方法

摘要

Provided are a cell separation and collection membrane capable of suppressing non-specific adsorption of cells while specifically adsorbing target cells; a culturing sheet and a culturing apparatus which use the membrane; and a cell separation and collection method. The cell separation and collection membrane included in the culturing sheet comprises: a support; a polymer site fixed to the support and having a changeable structure in accordance with a temperature; a cell adsorbing site bound to the polymer site, exposed relative to an outer surface of the support, and specifically adsorbing a target cell when the cell adsorbing site is brought into contact with a treatment solution containing the target cells; and a hydrophilic site exposed relative to the outer surface and to be brought into contact with the treatment solution.
机译:提供一种细胞分离收集膜,其能够抑制细胞的非特异性吸附,同时特异性地吸附靶细胞。使用该膜的培养片和培养装置;以及细胞分离和收集方法。培养片中所含的细胞分离收集膜包括:载体;和固定在载体上并根据温度具有可变结构的聚合物位点;与聚合物部位结合的细胞吸附部位,相对于支持体的外表面暴露,并且当细胞吸附部位与含有靶细胞的处理液接触时,特异性地吸附靶细胞。相对于外表面暴露并与处理溶液接触的亲水位点。

著录项

  • 公开/公告号US2016222339A1

    专利类型

  • 公开/公告日2016-08-04

    原文格式PDF

  • 申请/专利权人 HITACHI LTD.;

    申请/专利号US201314917115

  • 发明设计人 YASUHIKO TADA;YUI SUGITA;KEISUKE SHIBUYA;

    申请日2013-09-09

  • 分类号C12M1/00;C12M1/12;C12N5/09;C12N5/071;C12N5/0781;

  • 国家 US

  • 入库时间 2022-08-21 14:34:36

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