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NSAIDs-induced gastrointestinal mucosal disorder alleviator and manufacturing method thereof

机译:非甾体类抗炎药引起的胃肠道粘膜疾病缓解剂及其制造方法

摘要

A method of manufacturing a medical drug of alleviating damage of gastrointestinal mucosal induced by a non-steroidal anti-inflammatory drug, NSAID, the medical drug being able to induce anti-inflammatory effect of the NSAID and being able to alleviate damage induced by the NSAID includes dissolving trehalose and the NSAID into one or more solutions, so as to obtain an approximately homogenously-mixed liquid mixture of the trehalose and the NSAID; in which the liquid mixture contains an intermolecular compound with the trehalose and the NSAID; and drying the liquid mixture so as to obtain the medical drug.
机译:一种减轻非甾体类抗炎药NSAID引起的胃肠道粘膜损伤的药物的制造方法,该药物能够诱导NSAID的抗炎作用并且能够减轻由NSAID引起的损伤包括将海藻糖和NSAID溶解在一种或多种溶液中,以获得海藻糖和NSAID的近似均匀混合的液体混合物;其中所述液体混合物包含具有海藻糖和NSAID的分子间化合物;干燥该液体混合物以获得药物。

著录项

  • 公开/公告号US9452180B2

    专利类型

  • 公开/公告日2016-09-27

    原文格式PDF

  • 申请/专利权人 NEXT21 K.K.;

    申请/专利号US201414295154

  • 发明设计人 YUICHI TEI;NOBUO SASAKI;SHIGEKI SUZUKI;

    申请日2014-06-03

  • 分类号C07H3/04;A61K31/7016;A61K31/192;A61K31/196;A61K31/405;A61K31/5415;A61K31/616;A61K45/06;A61K47/26;

  • 国家 US

  • 入库时间 2022-08-21 14:31:02

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