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Dibenzofuran derivatives as inhibitors of fructose 1,6-bisphosphatase and methods of use thereof

机译:作为果糖1,6-双磷酸酶抑制剂的二苯并呋喃衍生物及其使用方法

摘要

The invention is directed to a compound according to formula (I). The compounds of formula (I) include prodrugs, pharmaceutically acceptable salts, stereoisomer mixtures, and enantiomers thereof. The invention is also directed to a pharmaceutical composition comprising a compound according to formula (I) and a pharmaceutically acceptable carrier and to methods for treating diabetes by administering such a pharmaceutical composition alone or in combination with other therapeutic agents. The invention is also directed to inhibitors of fructose-1,6-bisphosphatase.; embedded image
机译:本发明涉及式(I)的化合物。式(I)的化合物包括其前药,药学上可接受的盐,立体异构体混合物和对映异构体。本发明还涉及包含式(I)的化合物和药学上可接受的载体的药物组合物,并且涉及通过单独或与其他治疗剂组合施用这种药物组合物来治疗糖尿病的方法。本发明还涉及果糖-1,6-双磷酸酶的抑制剂。 “嵌入式图像”

著录项

  • 公开/公告号US9273021B2

    专利类型

  • 公开/公告日2016-03-01

    原文格式PDF

  • 申请/专利权人 EVAN R. KANTROWITZ;SABRINA HENG;

    申请/专利号US201013147964

  • 发明设计人 EVAN R. KANTROWITZ;SABRINA HENG;

    申请日2010-02-04

  • 分类号C07D307/91;A61P3/10;

  • 国家 US

  • 入库时间 2022-08-21 14:29:04

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