A medicament composition suitable for treating heart disease for parents, contained in a sealed container, pH value between 3.5-6.5, used for treating heart disease, and manufacturing method

摘要

An aqueous Pharmaceutical composition sterile, Ready to use, suitable for parenteral administration by infusion for the treatment of Heart conditions, packed in a Sealed container, and which has a pH between 3.5 and 6.5, which comprises (a) 100 mg / ml of 0.1 m hydrochloride Ethyl - 3 - [4 - (2 - hydroxy - 3 - isopropiiamino Phenylpropionate (hydrochloride) propoxy] esmoioi); (b) 0.01 to 0.5 m of a buffering agent; and (c) 1 to 100 mg / ml of an Osmotic Regulatory Agent selected from at least one of Sodium Chloride, dextrose, sodium bicarbonate, Calcium chloride, potassium chloride, SODIUM LACTATE Ringer's solution and Ringer's Solution iactada. A method for their Manufacture.Claim 2: the pharmaceutical Composition of claim 1, wherein the PH is between 4.5 and 5.5. Claim 3: the pharmaceutical composition according to claim 1 or 2, wherein the Buffering Agent comprises at least one characterized glutamate, acetate, Citrate, tartrate, benzoate, lactate, gluconate, phosphate and Glycine.Claim 6: the pharmaceutical composition according to claim 1, characterized in that it is free of propylene glycol and ethanol.