compound, pharmaceutical composition, method for treating a pi3k-related disease or disorder in an individual in need thereof, method for treating a mtor-mediated disease, method for treating both pi3k and hdac-mediated diseases

摘要

The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.