((1s, 2s, 4r) -4- {4 - (1s) -2,3-dihydro-1h-inden-1-ylamino -7h-pyrrolo 2,3-d pyrimidin-7 hydrochloride salt -yl} -2-hydroxycyclopentyl) methyl sulfamate

摘要

Disclosed is a compound of formula ( I ): crystalline forms thereof, and solvates thereof; pharmaceutical compositions comprising a pharmaceutically effective amount of the compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, and a pharmaceutically acceptable carrier or diluent; and the use of a compound of formula ( I ), or a crystalline form thereof, or a solvate thereof, for treating a patient suffering from, or subject to, a pathological condition capable of being ameliorated by inhibiting an E1 activating enzyme, particularly NAE, including, e.g., cancer.