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2 Components and methods of fatty acid prostate supply in subnorthern China

机译:2中国北方地区脂肪酸前列腺供应的组成和方法

摘要

Described herein are compositions comprising a prostaglandin FP receptor agonist (PFPRA) compound and a fatty acid ester (e.g., isopropyl myristate), optionally comprising an ointment base such as a hydrocarbon base (e.g., petroleum jelly) and/or an organic alcohol (e.g., propylene glycol), that, when topically applied to the skin, locally delivers a therapeutically effective amount of the PFPRA compound to subcutaneous fat under the skin, and methods of preparation. The therapeutic effect is, for example, reduction of the subcutaneous fat under the skin. Further provided are methods of reducing body fat in a subject comprising topically administering the composition to the subject.
机译:本文描述了包含前列腺素FP受体激动剂(PFPRA)化合物和脂肪酸酯(例如肉豆蔻酸异丙酯)的组合物,其任选地包含软膏剂基质,例如烃碱(例如凡士林)和/或有机醇(例如(例如,丙二醇),其局部施用于皮肤时,将治疗有效量的PFPRA化合物局部递送至皮肤下的皮下脂肪,以及制备方法。治疗效果是例如减少皮肤下的皮下脂肪。还提供了减少受试者体内脂肪的方法,其包括将组合物局部施用于受试者。

著录项

  • 公开/公告号CR20150652A

    专利类型

  • 公开/公告日2016-06-01

    原文格式PDF

  • 申请/专利权人 TOPOKINE THERAPEUTICS INC;

    申请/专利号CR20150652

  • 发明设计人 SINGER MICHAEL S;KALAYOGLU MURAT V;

    申请日2015-12-10

  • 分类号A61K9;A61K9/06;A61K31/5575;A61K47/06;A61K47/14;

  • 国家 CR

  • 入库时间 2022-08-21 14:26:36

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