Process for the preparation of (1s,3s,7s,10r,11s,12s,16r)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-(1e)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-17-oxa-4-azabicyclo14.1.0heptadecane-5,9-dione and intermediates thereof

摘要

The present invention relates to process for the preparation of (1 S,3 S,7S, 1 OR, 11S, 12S, 16R)-7,11 -dihydroxy-8,8,10,12,16-pentamethyl-3-[(lE)-1 -methyl-2-(2-methyl-4-thiazolyl)ethenyl]-17-oxa-4-azabicyclo[14.1.0]heptadecane-5,9-dione reesented by the following structural formula-1. Formula-1 The present invention also relates to a novel intermediate compound, which is useful for the preparation of compound of formula-1.