首页> 外国专利> HEMOSTATIC DRESSINGS WITH AN ANTIMICROBIAL ACTION BASED ON CHITOSAN HYDROGELS.

HEMOSTATIC DRESSINGS WITH AN ANTIMICROBIAL ACTION BASED ON CHITOSAN HYDROGELS.

机译:基于壳聚糖的具有止血作用的止血药。

摘要

The present invention discloses hemostatic dressings with an antimicrobial action based on chitosan hydrogels, which are thin and flexible foams with antimicrobial and absorbable hemostatic actions, based on chitosan. The hemostatic property is produced by positive charges of the chitosan which interact with the negative charges of the red blood cells, causing bleeding to stop, thereby reducing the risk of infection. In addition, by being biocompatible, said dressings activate and optimize the healing process. The invention also relates to a method for obtaining said hemostatic dressings, comprising the steps of freezing and lyophilizing the same for producing a porous three- dimensional matrix with biological, physical and mechanical characteristics that are improved with alginate and crosslinking agents. Due to the technical characteristics of the invention, the production costs as well as those of the final product are significantly reduced in comparison with the existing hemos tatic dressings, which are of exclusive military use in many cases, and are made of non-biocompatible materials, the cost is high and are not always available for commercial use in civil life or in the pre-hospital field.
机译:本发明公开了基于壳聚糖水凝胶的具有抗菌作用的止血敷料,其是基于壳聚糖的具有抗菌和可吸收止血作用的薄且柔软的泡沫。止血特性是由壳聚糖的正电荷与红细胞的负电荷相互作用而产生的,导致出血停止,从而降低了感染的风险。另外,通过具有生物相容性,所述敷料激活并优化了愈合过程。本发明还涉及一种用于获得所述止血敷料的方法,该方法包括将其冷冻和冻干的步骤,以生产具有藻酸盐和交联剂改善的具有生物学,物理和机械特性的多孔三维基质。由于本发明的技术特征,与现有的出血性敷料相比,其生产成本以及最终产品的生产成本大大降低,后者在许多情况下是专用于军事用途,并且由非生物相容性材料制成,成本很高,在民用生活或院前领域并不总是可用于商业用途。

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