Strategies to prevent and / or treat immune responses to soluble allophactors

摘要

An isolated immunogenic peptide comprising (i) a MHC class II restricted T cell epitope of a soluble alloantigen and (ii) a redox motif C- (X) 2- [CST] or [CST] - (X) 2- C, wherein said motif is immediately adjacent to said T cell epitope, or is separated from said T cell epitope by a connector of a maximum of seven amino acids, for use in prevention or suppression, in a subject waiting to receive, which is receiving or has received said soluble alloantigen from immune responses to said soluble alloantigen.