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IMMEDIATE-RELEASE TABLET FORMULATION, COMPOSITION FOR TABLETS AND METHOD FOR MANUFACTURING IMMEDIATE-RELEASE TABLET FORMULATION

机译:速释片剂的配方,片剂的组成和制造速释片剂的方法

摘要

Provided are: an immediate-release tablet formulation that contains casein and/or casein hydrolysate at a high concentration as an active ingredient and yet has excellent mechanical strength; a composition for the immediate-release tablet formulation, said composition having excellent tabletability; and a method for manufacturing the immediate-release tablet formulation using the composition. The immediate-release tablet formulation and the composition for the immediate-release tablet formulation comprise 50 mass% or more of casein and/or casein hydrolysate and lactose having a volume-average particle size of 50-300 μm inclusive, wherein the lactose content is 6.0-100 parts by mass per 100 parts by mass of casein and/or casein hydrolysate. The method for manufacturing the immediate-release tablet formulation comprises: a step for preparing the composition for the immediate-release tablet formulation as a mixture; a step for filling the mixture in a mortar and tabletting; and a step for taking out tablets thus tabletted from the mortar.
机译:提供:速释片剂,其含有高浓度的酪蛋白和/或酪蛋白水解物作为有效成分,并且具有优异的机械强度。用于速释片剂的组合物,所述组合物具有优异的压片性。以及使用该组合物制造速释片剂的方法。速释片剂制剂和用于该速释片剂制剂的组合物包含50质量%以上的酪蛋白和/或酪蛋白水解产物和乳糖,其体积平均粒径为50-300μm(含)。相对于每100质量份酪蛋白和/或酪蛋白水解物6.0-100质量份。用于制备速释片剂的方法包括:制备用于速释片剂的组合物的混合物的步骤;将混合物填充到研钵中并压片的步骤;以及从研钵中取出由此压片的片剂的步骤。

著录项

  • 公开/公告号WO2015186729A1

    专利类型

  • 公开/公告日2015-12-10

    原文格式PDF

  • 申请/专利权人 CALPIS CO. LTD.;

    申请/专利号WO2015JP66011

  • 发明设计人 KUBOTA AKIRA;

    申请日2015-06-03

  • 分类号A61K38;A61K9/20;A61K38/17;A61K47/26;A61P9/12;A61P25/28;A61P43;

  • 国家 WO

  • 入库时间 2022-08-21 14:20:13

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