RGMc Media composition for inducing stem cell comprising replusive guadiance molecule c and method for inducing stem cell using the same

摘要

The present invention relates to a stem cell inducing medium composition comprising RGMc as an active ingredient, and a stem cell inducing method using the same. RGMc binds to neogenin more than normal mouse embryos not treated with RGMc in neojenin-overexpressed mouse embryos, resulting in a high level of ICM cells expressing OCT3 / 4, SOX2 and Nanohog stem cell genes in blastocysts, And can be used as a medium composition for inducing stem cells using the same.