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Assessment of biological cells using the sequence of the entire genome and TREATMENT PLANNING ONCOLOGIC using said ASSESSMENT

机译:使用整个基因组的序列评估生物细胞,并使用所述评估方法进行肿瘤治疗规划

摘要

1. A method for identifying a tissue suspected cancerous tissue, the method comprising the following steps: a sample is treated with (10) the suspect tissue, or a space of a selected area of ​​an object (6) survey which (aq) suspected of containing the cancerous tissue, using an apparatus ( 14) genetic sequencing to produce suspected sequence (20), complete genome; treated sample (12) of the normal tissue selected from the place or area the test subject which (aq) presumably contains cancerous tissue by using the apparatus (14) of the genetic sequencing to produce normal sequence (22), complete genome; calculated (30) using a processor comparing the sequences of complete genomes metric by comparing the suspected sequence the complete genome of a normal sequence of the complete genome iopredelyayut using processor probability of containing the cancerous tissue sample suspected tissue based variants threshold calculated metric comparing the sequences of full genomov.2. The method of claim. 1, wherein the step of identifying (32) does not include identification, whether a tissue sample contains a particular type of cancer tkani.3. The method of claim. 1, wherein the step of identifying (32) does not include any identification of specific genetic variant in full surface genoma.4 suspected. The method of claim 1, wherein the step of identifying (32) comprises the following step:. Tag as a tissue sample or a cancerous tissue or a normal tissue based on the computed metric genoma.5 complete sequence comparison. The method of claim. 1, wherein the step
机译:1.一种用于识别可疑癌组织的组织的方法,该方法包括以下步骤:用(10)可疑组织或对象的选定区域的空间对样本进行处理(6)调查(aq )怀疑含有癌组织,使用装置(14)进行基因测序以产生可疑序列(20)的完整基因组;通过使用基因测序的装置(14)产生正常序列(22),完整的基因组,从正常受试者的被试部位或区域中选择的正常组织的经处理的样品(12),其中该受试者可能含有癌组织。 (30)使用处理器比较完整基因组序列的指标,通过比较可疑序列与完整基因组iopredelyayut正常序列的完整基因组的指标,使用包含癌变组织样品的处理器概率,基于可疑组织的变体阈值计算指标,比较序列完整的基因转移2。权利要求的方法。如图1所示,其中识别步骤(32)不包括识别组织样本是否包含特定类型的tkani.3癌症。权利要求的方法。如图1所示,其中鉴定步骤(32)不包括对可疑全表面基因瘤中特定遗传变异的鉴定。 2.根据权利要求1所述的方法,其中,所述识别步骤(32)包括以下步骤:根据计算出的度量基因组标记组织样本或癌组织或正常组织。5完整序列比较。权利要求的方法。 1,其中的步骤

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