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METHOD FOR PREDICTION OF HEMORRHAGIC FORMS OF DISEASE DEVELOPING IN PATIENTS, SUFFERING FROM ERYSIPELAS OF LOWER EXTREMITIES

机译:预测下肢红斑患者的疾病发展的出血形式的方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to method of prognosis of developing hemorrhagic forms of erysipelas in patients suffering from erysipelas of lower extremities. Method for prognosis of developing hemorrhagic forms of erysipelas in patients suffering from erysipelas of lower extremities (ELE), involving biochemical blood examination in patients with ELE in first three days from onset of clinical symptoms leptin level in blood serum, resistin and coagulogram are determined: APTT and fibrinogen; critical values of above indicators are assigned with points: leptin level increase from 51.7 to 57.9 ng/ml corresponds to 1 point; from 58.0 ng/ml and more - 2 points; increase of resisting level to 17.0 ng/ml corresponds to 1 point, while 17.1-20.0 ng/ml corresponds to 2 points; increase of coagulogram parameters: APTT 36 s and more corresponds to 0.5 points fibrinogen level 7 g/l or more corresponds to 0.5 points; then total adipokine coefficient (Kc) is calculated, equal to sum of points for each indicator; and if Kc is equal to 2-2.4 points, moderate risk of erysipelas hemorrhagic forms (HF) is prognosed; if Kc is equal to 2.5-2.9 points, high risk of erysipelas HP developing is prognosed; if Kc is equal to 3.0 or more points, extremely high risk of erysipelas HP developing is prognosed.;EFFECT: use of above method enables predicting erysipelas hemorrhagic forms developing at early stages of disease in patients suffering from erysipelas of lower extremities.;1 cl, 3 dwg, 2 tbl
机译:药物发明领域本发明涉及药物,即涉及下肢丹毒的患者发展出血形式丹毒的预后方法。确定患有下肢丹毒(ELE)的患者发展为出血型丹毒的方法,包括从临床症状发作开始的前三天对ELE患者进行生化血液检查,确定血清中瘦素水平,抵抗素和凝血图: APTT和纤维蛋白原;上述指标的临界值用点表示:瘦素水平从51.7 ng / ml增加到57.9 ng / ml相当于1个点。从58.0 ng / ml及以上-2分;抵抗水平提高到17.0 ng / ml相当于1点,而17.1-20.0 ng / ml则相当于2点。凝血参数增加:APTT 36 s或以上对应0.5点,纤维蛋白原水平7 g / l或以上对应0.5点;然后计算总脂肪因子(Kc),等于每个指标的总点数;如果Kc等于2-2.4点,则预示着中毒的丹毒出血形式(HF);如果Kc等于2.5-2.9点,则预示丹毒HP发生的高风险;如果Kc等于3.0或更高点,则预示着丹毒HP发生的极高风险。;效果:使用上述方法可以预测患有下肢丹毒的患者疾病早期的丹毒出血形式。; 1 cl ,3载重吨,2汤匙

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